Reaction of 1-Carbamoyl-3,4-Epoxy-4-Phenylpiperidines with Lewis Acids
作者:
FredM. Hershenson,
Leif Christensen,
期刊:
Synthetic Communications
(Taylor Available online 1981)
卷期:
Volume 11,
issue 8
页码: 615-625
ISSN:0039-7911
年代: 1981
DOI:10.1080/00397918108063634
出版商: Taylor & Francis Group
数据来源: Taylor
摘要:
A recent report1describing the facile rearrangement of piperidine epoxide, 6b, into 3-formyl-3-phenylpyrrolidine, 7b, with BF3etherate prompts us to present results obtained from our investigation of the reaction of 1-carbamoyl-3,4-epoxy-4-phenylpiperidines with several different Lewis Acids. Our interest in examining this particular reaction arose from a need to prepare 4-phenyl-3-piperidones, such as compound 3.
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