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COMPLEMENTARY NONPARAMETRIC ANALYSIS OF COVARIANCE FOR LOGISTIC REGRESSION IN A RANDOMIZED CLINICAL TRIAL SETTING

 

作者: CatherineM. Tangen,   GaryG. Koch,  

 

期刊: Journal of Biopharmaceutical Statistics  （Taylor Available online 1999）
卷期: Volume 9, issue 1  

页码: 45-66

 

ISSN:1054-3406

 

年代: 1999

 

DOI:10.1081/BIP-100100999

 

出版商: Taylor & Francis Group

 

关键词: Population average odds ratio;Proportional odds;Random imbalance of covariables;Stratified analyses;Variance reduction from covariance adjustment;Weighted least squares

 

数据来源: Taylor

 

摘要:

In the randomized clinical trial setting, controlling for covariates is expected to produce variance reduction for the treatment parameter estimate and to adjust for random imbalances of covariates between the treatment groups. However, for the logistic regression model, variance reduction is not obviously obtained. This can lead to concerns about the assumptions of the logistic model.

 

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