A Pilot Study of Primary-Care—Based Buprenorphine Maintenance for Heroin Dependence
作者:
O'ConnorPatrick G.,
OlivetoAlison H.,
ShiJulia M.,
TrifflemanElisa,
CarrollKathleen M.,
KostenThomas R.,
RounsavilleBruce J.,
期刊:
The American Journal of Drug and Alcohol Abuse
(Taylor Available online 1996)
卷期:
Volume 22,
issue 4
页码: 523-531
ISSN:0095-2990
年代: 1996
DOI:10.3109/00952999609001678
出版商: Taylor&Francis
关键词: Substance abuse;Opioid dependence;Buprenorphine maintenance
数据来源: Taylor
摘要:
The treatment of heroin dependence with opioid maintenance has traditionally employed methadone and more recently buprenorphine administered in traditional drug treatment settings. In this pilot study we evaluated buprenorphine maintenance for the treatment of heroin dependence in a program administered by primary-care providers in a primary-care setting. Seven patients were admitted to this nonblinded open-label pilot study and were offered 6 months of primary-care-based buprenorphine maintenance. Buprenorphine was administered in doses of 16 mg on Monday and Wednesday and 32 mg on Friday. Patients were seen weekly by primary-care providers and attended self-help meetings. Of the seven patients admitted to the study, five (71%) completed the 6-month pilot study and two (29%) were removed from the study. Urine toxicology data showed that the majority of urines tested were clear of opioids in four out of five patients who remained in treatment. These results suggest that primary-care-based opioid maintenance using buprenorphine shows promise as a new approach to the treatment of heroin dependence.
点击下载:
PDF (376KB)
返 回