Chronic Fatigue Syndrome: A Novel Disorder with Cutaneous Manifestations
作者:
A. Rebora,
F. Drago,
期刊:
Dermatology
(Karger Available online 1994)
卷期:
Volume 188,
issue 1
页码: 3-5
ISSN:1018-8665
年代: 1994
DOI:10.1159/000247075
出版商: S. Karger AG
关键词: Epstein-Barr virus;Chronic fatigue syndrome;Erythema multiforme
数据来源: Karger
摘要:
Persistent and disabling fatigue associated with low-grade fever and other constitutional symptoms, without any known disorder that accounts for it, is recognized as chronic fatigue syndrome (CFS). Skin lesions occur in 10–35% of patients, but their description is inaccurate. Recurrent aphthous stomatitis or persistent Epstein-Barr virus (EBV)-related erythema multiforme have also been reported. Patients may be diagnosed as having CFS only when they fulfill at least 2 major and 8 minor criteria. Major criteria are the presence of debilitating fatigue persisting or recurring for at least 6 months and the absence of any other medical disorder that may explain it. Although different viral or nonviral etiologies have been documented, evidence implicating EBV is gaining suppor
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