Experimental autoimmune uveoretinitis: a model system for immunointervention: a review
作者:
ForresterJ. V.,
LiversidgeJanet,
DuaH. S.,
DickA.,
HarperFiona,
McMenaminP. G.,
期刊:
Current Eye Research
(Taylor Available online 1992)
卷期:
Volume 11,
issue sup1
页码: 33-40
ISSN:0271-3683
年代: 1992
DOI:10.3109/02713689208999509
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Experimental autoimmune uveoretinitis (EAU) is a useful model of human posterior uveitis and as such, permits the analysis of strategies for immuno-intervention. Modulation of the autoimmune response may be attempted at the stages of induction of EAU, during homing of autoreactive lymphocytes to the target organ, the retina, or during the effector stage of the disease. This paper presents a brief overview of current immuno-therapeutic modalities and assesses the usefulness for extrapolation to human disease.
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