Two Cases of Choreatic Syndrome Caused by Polycythemia vera
作者:
V. Voiculescu,
D.A. Ionescu,
G. Lazar,
C. Alecu,
C. Predescu,
C. Popa,
A. Xenakis,
I. Marcu,
M. Ghitescu,
期刊:
European Neurology
(Karger Available online 1979)
卷期:
Volume 18,
issue 2
页码: 96-100
ISSN:0014-3022
年代: 1979
DOI:10.1159/000115061
出版商: S. Karger AG
关键词: Chorea;Polycythemia vera;Erythrocyte rheology;Cerebral circulation;Catecholamines
数据来源: Karger
摘要:
Two patients with choreatic syndromes caused by polycythemia vera recovered after treatment of the polycythemia by only two venesections: this proves that the syndrome is due to reversible alterations. Investigations of the cerebral circulation in one of the patients showed that blood flow was lowest in the grey matter at the basal region of the brain: this suggests that the alterations might mainly occur there. However, investigation of erythrocyte rheology, glucoses-phosphate dehydrogenase, serum concentrations of caeruloplasmin and serotonin, and urinary excretion of epinephrine, norepinephrine and vanillylmandehc acid gave normal results in both patients. There are therefore no indications as to the possible pathophysiology of these alterations. There are now 24 cases reported, including our 2 patients, which suggests that the association of these two diseases may not be so rare as supposed.
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