Systolic Time Intervals and Left Ventricular Function in Acute Myocardial Infarction
作者:
Paul,
Hamosh Jay,
Cohn Karl,
Engelman Martin,
Broder Edward,
期刊:
Circulation
(OVID Available online 1972)
卷期:
Volume 45,
issue 2
页码: 375-381
ISSN:0009-7322
年代: 1972
出版商: OVID
关键词: Stroke volume;Left ventricular end-diastolic pressure;Catecholamines;Congestive heart failure
数据来源: OVID
摘要:
Systolic time intervals (STI) were measured simultaneously with left ventricular pressure, right atrial pressure, and cardiac output in patients with acute myocardial infarction (AMI) within 24 hours of the onset of symptoms. Electromechanical systole (QS2) and left ventricular ejection time (LVET) were measured and preejection period (PEP) calculated and corrected for heart rate. LVET showed significant correlation with stroke volume (r = 0.62), confirming previous observations. Patients with significantly elevated left ventricular end-diastolic pressure (LVEDP) and clinical signs of congestive heart failure (CHF) usually exhibited a prolonged PEP when compared with normal subjects or patients with AMI who did not have signs of CHF. The normal PEP in the latter group might be due to adrenergic stimulation offsetting the effect of myocardial damage, although measurements of circulating catecholamines did not conclusively support this hypothesis. We conclude that STI are not reliable indices of left ventricular performance in AMI.
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