Morphology, histochemistry, and distribution of serotonin‐containing cells in tracheal epithelium of adult rabbit
作者:
Richard D. Dey,
Robert Echt,
Robert J. Dinerstein,
期刊:
The Anatomical Record
(WILEY Available online 1981)
卷期:
Volume 199,
issue 1
页码: 23-31
ISSN:0003-276X
年代: 1981
DOI:10.1002/ar.1091990104
出版商: Wiley Subscription Services, Inc., A Wiley Company
数据来源: WILEY
摘要:
AbstractWe have investigated morphologic and histochemical characteristics of serotonin‐containing epithelial cells in tracheas from adult rabbits, using the Falck‐Hillarp freeze‐dried formaldehyde vapor technique. An intracellular formaldehyde‐induced fluorescent substance was identified as serotonin by microspectrofluorometric techniques. Fluorescence microscopy and subsequent histochemical staining of the same sections demonstrated that serotonin‐containing cells were argentaffin‐, argyrophil‐, and ferric ferricyanide‐positive. The serotonin‐containing epithelial cells were more numerous in ventral than in dorsal aspects of trachea. The number of detectable fluorescent cells was reduced after reserpine administration but was not affected by injecting the amine precursor L‐dihydroxyphenylalanine (L‐DOPA). The emission peak of the fluorophore was not significantly shifted after L‐DOPA injections. The cells may regulate tracheobronchial‐pulmonary function by releasing serotonin or other as yet unidentified biolo
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