Use of cyclodextrins in capillary zone electrophoresis for the separation of optical isomers: Resolution of racemic tryptophan derivatives
作者:
Annalisa Nardi,
Luigia Ossicini,
Salvatore Fanali,
期刊:
Chirality
(WILEY Available online 1992)
卷期:
Volume 4,
issue 1
页码: 56-61
ISSN:0899-0042
年代: 1992
DOI:10.1002/chir.530040112
出版商: Alan R. Liss, Inc.
关键词: capillary zone electrophoresis;enantiomers;cyclodextrins;tryptophan derivatives
数据来源: WILEY
摘要:
AbstractIn this study capillary zone electrophoresis has been used for the separation of racemic tryptophan derivatives in their enantiomers. The effect of cyclodextrins with different shape, added to the background electrolyte, on the migration time of 10 compounds, including methyl tryptophan, hydroxy tryptophan, and tryptophan ester derivatives, has been studied. Furthermore, the effect of cyclodextrins with different shape and that of the composition of the background electrolyte on the enantiomer resolution are discussed. Among different cyclodextrins used α‐cyclodextrin and heptakis(2,6‐di‐O‐methyl)‐β‐cyclodextrin were found to possess the best complexing capacity and thus the resolution power toward analy
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