Rapid‐Sequence Orotracheal IntubationA Comparison of Three Techniques
作者:
Sanford Silverman,
Robert Culling,
Robert Middaugh,
期刊:
Anesthesiology
(OVID Available online 1990)
卷期:
Volume 73,
issue 2
页码: 244-248
ISSN:0003-3022
年代: 1990
出版商: OVID
关键词: Intubation: rapid-sequence.;Neuromuscular relaxants: succinylcholine; vecuronium.;Pharmacodynamics: “The Timing Principle;” “The Priming Principle.”
数据来源: OVID
摘要:
The authors compared tracheal intubating conditions using three techniques for rapid-sequence orotracheal intubation. Sixty patients were randomly assigned to one of three groups: priming with vecuronium (0.01 mg/kg priming dose, 4-min priming interval, 0.14-mg/kg intubating dose along with thiopental 4–6 mg iv); timing with vecuronium (0.15-mg/kg intubating dose given before thiopental and timed to weakness of hand grip); and succinylcholine (1.5 mg/ kg). Blinded intubators graded intubating conditions 60 s after the induction of anesthesia with thiopental. Intubation scores in the succinylcholine group were significantly better than in the priming group (P= 0.009). Intubation scores of the succinylcholine and the timing groups were not significantly different. Use of the timing principle for rapid-sequence orotracheal intubation is a reliable alternative in cases where succinylcholine is contraindicated.
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