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L-5-Hydroxytryptophan in Depression: the First Substitution Therapy in Psychiatry?

 

作者: L.J. van Hiele,  

 

期刊: Neuropsychobiology  （Karger Available online 1980）
卷期: Volume 6, issue 4  

页码: 230-240

 

ISSN:0302-282X

 

年代: 1980

 

DOI:10.1159/000117757

 

出版商: S. Karger AG

 

关键词: ‘Therapy-resistant’ depressions;Central serotonin (5-HT) defìciency;Substitution therapy with L-5-hydroxytryptophan

 

数据来源: Karger

 

摘要:

99 ‘therapy-resistant’ depressive out-patients were treated with l-5-hydroxytrypto-phan combined with the peripheral decarboxylase inhibitor, carbidopa. This treatment produced an astonishing recovery without side effects in some 50% of the patie

 

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