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Effects of Sodium Nitroprusside and Other Pentacyanonitrosyl Complexes on Platelet Aggregation

 

作者: Erika Glusa,   F. Markwardt,   J. Stürzebecher,  

 

期刊: Pathophysiology of Haemostasis and Thrombosis  （Karger Available online 1974）
卷期: Volume 3, issue 5-6  

页码: 249-256

 

ISSN:1424-8832

 

年代: 1974

 

DOI:10.1159/000214063

 

出版商: S. Karger AG

 

关键词: Platelet aggregation;Pentacyanonitrosyl complexes

 

数据来源: Karger

 

摘要:

The influence of sodium nitroprusside (SNP) and other nitric oxide complexes on platelet function is studied. SNP inhibits platelet aggregation and the release reaction, while pentacyanonitrosyl complexes of manganese, tungsten, and molybdenum are ineffective. Since nitrosylperchlorate exerts the same inhibitory effect on platelet aggregation the nitrosyl cation is supposed to be the constituent of SNP responsible for inhibition.

 

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