Correlations of Topographical EEG Features with Clinical Severity in Mild and Moderate Dementia of Alzheimer Type
作者:
R. Chiaramonti,
G.C. Muscas,
M. Paganini,
Th.J. Müller,
A.J. Fallgatter,
V. Versari,
W.K. Strik,
期刊:
Neuropsychobiology
(Karger Available online 1997)
卷期:
Volume 36,
issue 3
页码: 153-158
ISSN:0302-282X
年代: 1997
DOI:10.1159/000119375
出版商: S. Karger AG
关键词: Topographical EEG analysis;Mini Mental State examination;Global deterioration scale;Fast Fourier transformation analysis
数据来源: Karger
摘要:
Quantitative electroencephalography (qEEG) and the Folstein Mini Mental State examination (MMSE) were obtained from 31 patients affected by probable dementia of Alzheimer’s type (DAT). qEEG data were examined both by spectral analysis (Fast Fourier Transformation) and by single frequency band topographical centroid, and compared with those of 24 healthy subjects of the same age group. DAT patients were found to have higher absolute power in the slow (delta and theta) frequency bands. Quantitative topographical assessment showed significantly more anteriorly located centers of gravity for the alpha and beta activity. Only alpha anteriorization was correlated with the degree of cognitive impairment as measured by the global deterioration scale and MMSE. It is concluded that quantitative topographical assessment was successful for the statistical handling of the EEG power maps, and to identify a potential parameter for the functional staging of the diseas
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