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A Counter Antigonadotrophic Effect of Melatonin in Male Rats

 

作者: R.J. Reiter,   D.E. Blask,   Mary K. Vaughan,  

 

期刊: Neuroendocrinology  （Karger Available online 1975）
卷期: Volume 19, issue 1  

页码: 72-80

 

ISSN:0028-3835

 

年代: 1975

 

DOI:10.1159/000122427

 

出版商: S. Karger AG

 

关键词: Pineal gland;Melatonin;Luteinizing hormone;Prolactin;Blinding;Anosmia;Rat

 

数据来源: Karger

 

摘要:

Blinding and anosmia in male rats is followed by retarded bodily development, reduced weights of the gonads and adnexa, and depressed levels of pituitary luteinizing hormone and prolactin. The effects of dual sensory deprivation are negated, for the most part, by either pinealectomy or the weekly subcutaneous implantation of melatonin (in beeswax). This is the first report that melatonin negates the antigonadotrophìc influence of the rat pineal gland

 

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