Polycystic Kidney Disease: I. Etiology and Pathogenesis
作者:
GranthamJared J.,
期刊:
Hospital Practice
(Taylor Available online 1992)
卷期:
Volume 27,
issue 3
页码: 51-59
ISSN:2154-8331
年代: 1992
DOI:10.1080/21548331.1992.11705379
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Geneticists and cell biologists are simultaneously studying the disease's underlying mechanisms. Although a great many questions remain about cyst formation and its role in kidney failure, three fundamental constructs on its etiology and pathogenesis have been generated: renal tubular epithelial proliferation, fluid accumulation, and remodeling of the extracellular matrix.
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