SummaryGranulocytic sarcoma or chloroma is defined as an extramedullar solid tumor, composed of granulocytic precursor cells at various levels of differentiation. Granulocytic sarcoma is mostly associated with acute and chronic leukemia, rarely with polycythemia vera and myelofibrosis. The use of special immunohistochemical stains is mandatory, because this tumor is often misdiagnosed as malignant lymphoma.We report two cases of granulocytic sarcoma (tonsil and ovary) associated with chronic myelogenous leukemia. We describe the first reported association of atypical CML and granulocytic sarcoma.