Permanent Loss of Ultrafiltration Capacity of the Peritoneum in Long-Term Peritoneal Dialysis: An Epidemiological Study
作者:
A. Slingeneyer,
B. Canaud,
C. Mion,
期刊:
Nephron
(Karger Available online 1983)
卷期:
Volume 33,
issue 2
页码: 133-138
ISSN:1660-8151
年代: 1983
DOI:10.1159/000182927
出版商: S. Karger AG
关键词: Maintenance peritoneal dialysis;End-stage renal disease;Intermittent peritoneal dialysis;Continuous ambulatory peritoneal dialysis;Ultrafiltration;Peritonitis
数据来源: Karger
摘要:
Permanent loss of the ultrafiltration (UF) capacity of the peritoneum has been observed with an increasing frequency among our patients treated by long-term intermittent (IPD) and/or continuous ambulatory peritoneal dialysis (CAPD).The analysis of various characteristics of our PD population (patients age, dialysis techniques, peritoneal infection rate and treatment duration) indicates that the incidence of this complication increases exponentially with the duration of PD, the loss of UF capacity being observed after a shorter period in CAPD than in IPD. These observations suggest that long-term irrigation of the peritoneal cavity leads to a progressive deterioration of the peritoneum resulting in its altered permeability with loss of the ability to ultrafiltrate; the cause of this abnormality is as yet unknown.
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