Testicular Reaction to Prolonged Exposure to Nitrous Oxide
作者:
Benjamin,
Kripke Asher,
Kelman Narendra,
Shah Karoly,
Balogh Alfred,
期刊:
Anesthesiology
(OVID Available online 1976)
卷期:
Volume 44,
issue 2
页码: 104-113
ISSN:0003-3022
年代: 1976
出版商: OVID
关键词: Anesthetics;gases;nitrous oxide; Spermatogenesis
数据来源: OVID
摘要:
Maie LEW/f Mai rats were exposed to an atmosphere of 20 per cent N2O, 20 per cent O2, and 60 per cent N2for a maximum of 35 days. Evidence of injury to the seminiferous tubules was found in some animals by the second day By 14 days, such damage was found in all animals, the toxic effect was confined to the spermatogenic cells, with consequent reduction in mature spermatozoa and appearance of multinucleated forms, Other cells within the testes were resistant to damage. Recovery of spermatogenesis occurred apparatus. after return to room air for more than three days, Serum testosterone levels were not significantly affected during the prolonged exposure.
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