ObjectiveTo identify prognostic indicators for geriatric patients discharged from an acute care hospital.DesignProspective observational study.SettingBase line assessment at discharge from an acute care hospital; reassessment after 1 year at home.PatientsOne hundred‐seventy‐eight consecutive patients over 70 years of age (mean age ± SD = 75.6 ± 13.1 years, range 70–95 years, 52% males); 56% were dependent in one or more Activities of Daily Living, 21% had abnormal Mini Mental State Scores.Main Outcome Measuresmortality, increasing physical dependence, health care utilization.ResultsMortality was directly related to a low ADL score at hospital discharge (Odds Ratio = 3.31, Confidence Limits = 1.91–5.75), neoplastic diseases (OR = 3.59, CL = 2.01–6.43), cardiovascular diseases (OR = 2.47, CL = 1.40–4.36), and drug use, expressed as the total number of individual preparations prescribed at discharge (OR = 1.72, CL = 1.05–2.83). Low ADL score, cardiovascular and neoplastic diseases were also predictive of increasing physical dependency. The use of health care services, quantified by an appropriately designed score, did not correlate with any of the baseline variables, with the implication that the use of the health care services was not proportional to the need for care. Conclusions: Elderly subjects at major risk of death and disability can be easily identified at discharge by a simple assessment of their medical and f