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Hazards of Epinephrine in Transsphenoidal Pituitary Surgery

 

作者: Y. Chelliah,   Pirjo Manninen,  

 

期刊: Journal of Neurosurgical Anesthesiology  (OVID Available online 2002)
卷期: Volume 14, issue 1  

页码: 43-46

 

ISSN:0898-4921

 

年代: 2002

 

出版商: OVID

 

关键词: Epinephrine;Transsphenoidal pituitary surgery;Hypophysectomy;Hypertension;Myocardial infarct

 

数据来源: OVID

 

摘要:

A 79-year-old woman with no history of myocardial ischemia presented with symptoms of pituitary apoplexy for which an urgent transsphenoidal resection of the pituitary gland was undertaken. The nasal passages were prepared with topical application of epinephrine followed by injection of what was presumed to be 1% lidocaine containing 10 &mgr;g/ml−1of epinephrine. After only 1.5 mL of the solution had been injected, she developed a hypertensive crisis, which was immediately treated. Postoperatively, she developed a myocardial infarction. The risks associated with the use of vasopressors are reviewed and suggestions for their safe use are presented.

 

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