The purpose of this study was to determine the influence of demographic characteristics, including ethnicity, socioeconomic status, marital status, and number of children, as well as menopausal status, physical symptoms, and psychological symptoms on midlife women's attitudes toward menopause. A random sample of 149 women, aged 35 to 65 and stratified by occupation, age, and race, was selected from employee lists. A 20-item, 7-point semantic differential Menopause Attitude Scale was admiislered. Menopausal status was determined by self-report and serum hormone levels of estradiol and follicle stimulating hormone (FSH). Symptoms were assessed by a 28-item Symptom Index, the Center for Epidemiologic Studies Depression Scale (CES-D) and the Bradbum Affect Balance Scale. Overall the majority of women, regardless of ethnicity or socioeconomic status, had neutral feelings toward menopause. Postmenopausal women reported the most positive attitudes toward menopause, which may indicate that once women have gone through menopause they find it to be less troubling than they anticipated earlier in life. Negative attitudes toward menopause were related to psychological symptoms with higher scores on the depression scale, suggesting that these women may be at higher risk for a difficult midlife transition.