Premature Ovarian Failure: Its Relationship to Autoimmune Disease
作者:
MICHAEL ALPER,
PETER GARNER,
期刊:
Obstetrics & Gynecology
(OVID Available online 1985)
卷期:
Volume 66,
issue 1
页码: 27-30
ISSN:0029-7844
年代: 1985
出版商: OVID
数据来源: OVID
摘要:
Thirty-three patients with the diagnosis of chromosomally competent premature ovarian failure were reviewed for evidence of autoimmune disease. Thirty-nine percent of subjects had an associated autoimmune disorder, of which thyroid disease was the most common. One patient had vitiligo and one had adrenal insufficiency. A family history of autoimmune disease was elicited from 18% of subjects, all of whom proved to have an autoimmune disease themselves. From these findings, and a review of other studies, the authors conclude that an associated autoimmune disease, or other evidence of autoimmunity, is present in 30 to 50% of patients with premature ovarian failure.
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