Lectin binding in retinoblastoma
作者:
BardensteinDavid S.,
RodriguesMerlyn M.,
AlroyJoseph,
BrownsteinSeymour,
期刊:
Current Eye Research
(Taylor Available online 1987)
卷期:
Volume 6,
issue 9
页码: 1141-1150
ISSN:0271-3683
年代: 1987
DOI:10.3109/02713688709034887
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Lectins were used as cytochemical probes to examine the relationship between normal retina and retinoblastoma. Cases of retinoblastoraa in which there were either Fiexner-Wintersteiner rosettes or fleurettes accompanied by nontumorous retina were studied with ten biotinylated lectins. Pineal and ocular tumors from cases of trilateral retinoblastoma were also studied. Con-A, LCA, PNA, WGA and RCA-I labeled tissue of each type to varying degrees, while BS-I, DBA, SBA, S-WGA and UEA-I bound neither tumor nor retina. The high degree of binding homology suggests biochemical as well as structural similarities between these tissues.
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