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Dasytrichone, A Novel Flavone From Dasymaschalon Trichophorum With Cancer Chemopreventive Potential

 

作者: Yong-Long Liu,   DavidK. Ho,   JohnM. Cassady,   CharlesE. Cottrell,   Jun Liang,   Jon Clardy,   VanessaM. Cook,   WilliamM. Baird,  

 

期刊: Natural Product Letters  （Taylor Available online 1992）
卷期: Volume 1, issue 3  

页码: 161-165

 

ISSN:1057-5634

 

年代: 1992

 

DOI:10.1080/10575639208048906

 

出版商: Taylor & Francis Group

 

关键词: Dasytrichone;Dasymaschalon Trichophorum;Annonaceae;Benzo[A]Pyrene Metabolism;Flavone;13C-,1h- Nmr;X-Ray Crystallography

 

数据来源: Taylor

 

摘要:

Dasytrichone, A Novel Flavone With An Unusual A-Ring Substitution Pattern Was Isolated From The Stems And Leaves OfDasymaschalon TrichophorumMerr. (Family Annonaceae). Its Structure Was Established By Spectroscopic Methods And Single Crystal X-Ray Crystallography. Dasytrichone Inhibits The Metabolism Of The Carcinogen Benzo[A]Pyrene By Hamster Embryo Cell Cultures, Suggesting That It Warrants Further Evaluation As A Potential Chemopreventive Agent.

 

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