Exposure to well water and pesticides in Parkinson's disease: A case‐control study in the madrid area
作者:
Félix Javier Jiménez‐Jiménez,
Dolores Mateo,
Santiago Giménez‐Roldán,
期刊:
Movement Disorders
(WILEY Available online 1992)
卷期:
Volume 7,
issue 2
页码: 149-152
ISSN:0885-3185
年代: 1992
DOI:10.1002/mds.870070209
出版商: Wiley Subscription Services, Inc., A Wiley Company
关键词: Parkinson's disease;Etiology;Well water exposure;Pesticides;Epidemiology
数据来源: WILEY
摘要:
AbstractPast exposure to well water and pesticides was assessed in 128 unselected Parkinson's disease (PD) patients and 256 age and sex‐matched controls. All were residents in a defined urban area of Madrid, Spain. In keeping with other reports, we found that exposure to well water might be a factor associated with the likelihood of developing PD, though only prolonged exposures of 30 years or longer were significantly different between PD and controls (p<0.02). In contrast, past exposure to pesticides did not appear to be associated with an increased risk of developing PD. Prolonged well water drinking antedating the development of PD was not associated with early onset of the disease, nor did such cases progress to greater disability. Future casecontrol studies addressing prolonged well water consumption as a risk factor in PD should look for differences in the content of substances other than pesticides in the water as determined by the source of water to which patients may have been specifically expose
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