A Protein crystallography beam line using MIRRORCLE‐6X, which is a compact synchrotron for hard x‐ray production, is under construction. Since MIRRORCLE‐6X provides hard x‐ray with high brightness, it is suitable for x‐ray source of accurate protein crystallography research in a small laboratory.The divergent x‐ray emitted from a target is focused by a condensing mirror. The mirrors used for the condensing mirror are a multi layer mirror of Wolter type and a rotating ellipsoidal mirror. Photon energies dispersed by them are set to the K‐edge of Zn and of Se, respectively. The flux at a focusing point is expected to be 103∼ 104times larger than that without the condensing mirror. The focusing size is less than 100 &mgr;m of diameter. The x‐ray after the mirror is transformed to parallel beam using a Fresnel zone plate and irradiated on a protein crystal. The diffraction figure is detected by the an imaging‐plate detector. © 2004 American Institute of Physics