Methylphenidate Augmentation Therapyin Schizophrenia
作者:
MARY CARPENTER,
BERTRAND WINSBERG,
LUIS CAMUS,
期刊:
Journal of Clinical Psychopharmacology
(OVID Available online 1992)
卷期:
Volume 12,
issue 4
页码: 273-275
ISSN:0271-0749
年代: 1992
出版商: OVID
数据来源: OVID
摘要:
Eight schizophrenic inpatients participated in a 2-week double-blind crossover study to test the efficacy of methylphenidate treatment for patients on a stabilized neuroleptic dose. All were young men with a childhood history of hyperactivity. The instruments used, the Brief Psychiatric Rating Scale, Scale for Assessment of Positive Symptoms, Scale for Assessment of Negative Symptoms, and Nurses Observation Scale for Inpatient Evaluation, showed no significant differences between stimulant and placebo conditions. One patient suffered a repeated pressor effect and was removed from the protocol. However, staff and self-report found some improvement in 3 patients and a slight worsening in 1.
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