Development of the rabbit appendix
作者:
Michele Barg,
Laurence R. Draper,
期刊:
Cells Tissues Organs
(Karger Available online 1977)
卷期:
Volume 98,
issue 1
页码: 106-115
ISSN:1422-6405
年代: 1977
DOI:10.1159/000144786
出版商: S. Karger AG
关键词: Gut-associated lymphoid tissues;Central and peripheral lymphoid tissues;Lymphoepithelial structure
数据来源: Karger
摘要:
The progressive lymphoepithelial development of the rabbit appendix was examined by light and electron microscopy. At 5 days postnatally, the appendix wall primitively resembles the mature organ but lacks both the discrete lymphoid organization and most cell types. The dome appears to be the first recipient of lymphoid cells. By 18 days the lymphoid nodule has become compartmentalized and lymphoid. The epithelium, although not fully developed, is in contact with the lymphocytes of the dome. The 5-week-old appendix has all the lymphoepithelial components of the adult but lacks the size of the mature organ. At all ages reported, plasma cells and dendritic cells are absent. Bacteria, thought to be essential to appendiceal lymphoid development, are not apparent at 5 or 18 days. The features common to central or peripheral lymphoid tissues are discussed.
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