Antioxidant- Influenced Alterations in Glutathione Reductase Activity in Different Age Groups of Male Mice
作者:
S.C. Khanna,
S.K. Garg,
Suraj P. Sharma,
期刊:
Gerontology
(Karger Available online 1992)
卷期:
Volume 38,
issue 1-2
页码: 9-12
ISSN:0304-324X
年代: 1992
DOI:10.1159/000213301
出版商: S. Karger AG
关键词: Antioxidant;Butylated hydroxy anisole;Glutathione reductase;Mice;Propyl gallate;α-Tocopherol
数据来源: Karger
摘要:
The glutathione reductase activity was estimated in brain and liver of male mice of different age groups fed on butylated hydroxy anisole (BHA), propyl gallate (PG) and α-tocopherol (TP). A significant increase in glutathione reductase activity was observed with TP during all the phases (pre-reproductive, reproductive and post-reproductive). Antioxidants enhanced the enzyme activity in both the tissues with the exception of BHA in brain during reproductive and PG in liver during pre-reproductive phases respectively. The enhanced reducing potential of the cell in terms of added bioconversion of GSSG to GSH may account for increase in longevity on antioxidant treatment
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