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HLA Phenotype and Haplotype Frequencies in the Cantabria (Middle North Spain) Population

 

作者: R. Calvet,   J.M. Pastor,   R. Fernandez,   A. Zubizarreta,   J.L. Romero,  

 

期刊: Human Heredity  （Karger Available online 1991）
卷期: Volume 41, issue 5  

页码: 324-329

 

ISSN:0001-5652

 

年代: 1991

 

DOI:10.1159/000154020

 

出版商: S. Karger AG

 

关键词: Human leukocyte antigen;Gene frequencies;Haplotype frequencies;Spanish population (Cantabria)

 

数据来源: Karger

 

摘要:

The gene and haplotype frequencies of the HLA-A and -B locus antigens were determined in 502 unrelated individuals from Cantabria (middle North Spain). Our results were compared with those reported for other European and Spanish populations. The haplotypes with significant linkage disequilibrium were also analyzed in various Spanish population samples in order to establish possible relationships with geographic situation and historical events.

 

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