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Role of the kidneys in elimination of glucagon, insulin, secretin and somatostatin in the rat

 

作者: H. A. EL MUNSHID,   J. J. HOLST,   I. LUNDQUIST,   G. LUNDQVIST,   O. B. SCHAFFALITZKY MUCKADELL,   R. HÄKANSON,  

 

期刊: Acta Physiologica Scandinavica  （WILEY Available online 1983）
卷期: Volume 117, issue 1  

页码: 27-31

 

ISSN:0001-6772

 

年代: 1983

 

DOI:10.1111/j.1748-1716.1983.tb07175.x

 

出版商: Blackwell Publishing Ltd

 

关键词: Renal elimination;glucagon;insulin;secretin;somatostatin

 

数据来源: WILEY

 

摘要:

Immunoreactive plasma glucagon and secretin in the rat was elevated 48 hours after nephrectomy and ureteral ligation. Since kidneys obstructed by ureteral ligation were unable to remove glucagon and secretin from the blood, renal handling of glucagon and secretin must include glomerular filtration. Insulin and somatostatin levels were significantly elevated 48 hours after nephrectomy, but not after ureteral ligation, indicating partial uptake from peritubular capillaries.

 

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