首页   按字顺浏览 期刊浏览 卷期浏览 Specific metaphase and interphase detection of the breakpoint region in 8q24 of burkitt...
Specific metaphase and interphase detection of the breakpoint region in 8q24 of burkitt lymphoma cells by triple‐color fluorescence in situ hybridization

 

作者: Thomas Ried,   Christoph Lengauer,   Thomas Cremer,   Joop Wiegant,   Anton K. Raap,   Mels Van Der Ploeg,   Peter Groitl,   Martin Lipp,  

 

期刊: Genes, Chromosomes and Cancer  （WILEY Available online 1992）
卷期: Volume 4, issue 1  

页码: 69-74

 

ISSN:1045-2257

 

年代: 1992

 

DOI:10.1002/gcc.2870040109

 

出版商: Wiley Subscription Services, Inc., A Wiley Company

 

数据来源: WILEY

 

摘要:

AbstractTriple fluorescence in situ hybridization with a plasmid DNA library from sorted human chromosomes 8 in combination with bacteriophage clones flanking the breakpoint in 8q24 of the Burkitt lymphoma cell line Jl was used for the specific delineation of this breakpoint in individual tumor cells. With this approach, tumor‐specific breakpoints in translocation chromosomes can be detected at all stages of the cell cycle with high specificit

 

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