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Titanium (O) Reagents; 4. A selective and efficient reduction of nitropyridine derivatives

 

作者: Marek Malinowski,  

 

期刊: Bulletin des Sociétés Chimiques Belges  (WILEY Available online 1988)
卷期: Volume 97, issue 1  

页码: 51-54

 

ISSN:0037-9646

 

年代: 1988

 

DOI:10.1002/bscb.19880970109

 

出版商: Wiley‐VCH Verlag GmbH&Co. KGaA

 

数据来源: WILEY

 

摘要:

AbstractFollowing the successful applications of a titanium (O) slurry in the deoxygenation of aromatic N‐oxides, we attempted to achieve this method for the reduction of a nitro‐ group in pyridine derivatives. In general, only aminopyridine derivatives were formed in 85‐98% yield.The advantage of this excellent reducing agent consists in mild reaction conditions and high yields of products, as well as in the selectivity of the rea

 

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