Titanium (O) Reagents; 4. A selective and efficient reduction of nitropyridine derivatives
作者:
Marek Malinowski,
期刊:
Bulletin des Sociétés Chimiques Belges
(WILEY Available online 1988)
卷期:
Volume 97,
issue 1
页码: 51-54
ISSN:0037-9646
年代: 1988
DOI:10.1002/bscb.19880970109
出版商: Wiley‐VCH Verlag GmbH&Co. KGaA
数据来源: WILEY
摘要:
AbstractFollowing the successful applications of a titanium (O) slurry in the deoxygenation of aromatic N‐oxides, we attempted to achieve this method for the reduction of a nitro‐ group in pyridine derivatives. In general, only aminopyridine derivatives were formed in 85‐98% yield.The advantage of this excellent reducing agent consists in mild reaction conditions and high yields of products, as well as in the selectivity of the rea
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