A New Model of ExperimentalBacteroides fragilisInfection in Mice and Rats
作者:
Marisa Berti,
Elsa Rossi,
Giampaolo Candiani,
Vittorio Arioli,
期刊:
Chemotherapy
(Karger Available online 1982)
卷期:
Volume 28,
issue 3
页码: 213-217
ISSN:0009-3157
年代: 1982
DOI:10.1159/000238079
出版商: S. Karger AG
关键词: Bacteroides fragilis;Experimental infection;Granuloma pouch
数据来源: Karger
摘要:
We describe a method, based on Selye’s granuloma pouch, for establishing reproducible Bacteroides fragilis infections in both mice and rats starting from rather low inocula. The infected pouches resemble abscesses and phlegmons. This model is promising for studies of antibiotic therapy in that both bacterial kinetics and antibiotic levels can be followed in the exudate
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