The Relation between Tetanic Fade and Receptor Occlusion in the Presence of Competitive Neuromuscular Block
作者:
B E Waud,
D R Waud,
期刊:
Anesthesiology
(OVID Available online 1971)
卷期:
Volume 35,
issue 5
页码: 456-464
ISSN:0003-3022
年代: 1971
出版商: OVID
关键词: Competitive neuromuscular block;Tetanus;Fade;Receptor occlusion;Margin of safety;d-Tubocurarine;Succinylcholinc.)
数据来源: OVID
摘要:
The relation between receptor occlusion by a competitive neuromuscular blocking agent and fade of an indirectly elicited tetanus at frequencies of 30, 100 and 200/sec has been determined. Tetanic fade at 30/sec returned to normal when one-fifth to one-quarter of the receptors became available, and thus recovery approximated closely that of the single twitch response. The tetanic fade at 100/sec was not normal unless half the receptor pool was available, and a normal response at 200/sec required two-thirds of the pool. It is suggested that recovery of the response to tetanic stimulation at 100/sec would provide a practical index of adequate recovery from curarization
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