Light induced shift and binding of S-antigen in retinal rods
作者:
BroekhuyseR. M.,
TolhuizenE. F. J.,
JanssenA. P. M.,
WinkensH. J.,
期刊:
Current Eye Research
(Taylor Available online 1985)
卷期:
Volume 4,
issue 5
页码: 613-618
ISSN:0271-3683
年代: 1985
DOI:10.3109/02713688508999993
出版商: Taylor&Francis
数据来源: Taylor
摘要:
S-antigen has been quantitated in bovine and rat retina by electroimmunoassay. The molar ratios S-antigen to rhodopsin in photoreceptor cells were close to 1:1.Immunofluorescence studies show that light induces a shift of S-antigen towards the rod outer segments where it concentrates. Assays indicate that S-antigen becomes largely water insoluble but detergent soluble under these conditions. On basis of previous ultrastructural and present results, this has been interpreted as a light induced binding of S-antigen to the rod outer segment membranes.The data support evidence from literature that S-antigen interacts with (rhod)opsin and we conclude that S-antigen plays a major role in the phototransduction process.
点击下载:
PDF (458KB)
返 回