Nausea is a common adverse side-effect frequently encountered in patients receiving PUVA therapy. A prospective study was done in those patients whose nausea was not controlled with usual therapeutic agents or suggestions. A total of 17 patients were entered into the study and placed on metoclopramide in varying doses on the day of PUVA therapy. Nausea was assessed by means of a visual analogue scale. In all patients studied, significant benefit and control of nausea was achieved with few side-effects seen.