Control of Intractable Spasticity with Intrathecal Morphine Sulfate
作者:
Donald Erickson,
Jo Lo,
Margi Michaelson,
期刊:
Neurosurgery
(OVID Available online 1989)
卷期:
Volume 24,
issue 2
页码: 236-238
ISSN:0148-396X
年代: 1989
出版商: OVID
关键词: Spasticity;Morphine sulfate;Intrathecal therapy
数据来源: OVID
摘要:
&NA;Three years ago we reported our preliminary results regarding treatment of intractable spasticity with use of intrathecal morphine. This paper is a follow‐up report of 12 patients who underwent implantation of a pump or reservoir for delivery of intrathecal morphine sulfate for control of spasticity. Our primary concern initially was that patients would ultimately become drug tolerant and lose the beneficial effect of the morphine. Only one of these 12 patients has developed drug tolerance. The longest follow‐up period has been 4.3 years, and this patient has maintained excellent control of his spasticity with a stable dose of 2 mg of morphine daily. (Neurosurgery24:236‐238, 1989)
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