Deanol, Lithium and Placebo in the Treatment of Tardive Dyskinesia
作者:
A. Jus,
A. Villeneuve,
J. Gautier,
K. Jus,
C. Villeneuve,
P. Pires,
R. Villeneuve,
期刊:
Neuropsychobiology
(Karger Available online 1978)
卷期:
Volume 4,
issue 3
页码: 140-149
ISSN:0302-282X
年代: 1978
DOI:10.1159/000117629
出版商: S. Karger AG
关键词: Tardive dyskinesia;Deanol;Lithium carbonate;Dopaminergic-cholinergic balance in striatum
数据来源: Karger
摘要:
A double-blind crossover study on the effects of deanol and lithium carbonate was conducted on a sample of 29 chronic schizophrenic patients with tardive dyskinesia. In addition to his usual treatment with different neuroleptics, each patient received during an 8-week period either deanol, lithium carbonate or placebo. A 4-week wash-out period was inserted between each of the 8-week periods of experimental treatment of the tardive dyskinesia. The administration of either deanol, lithium carbonate or placebo added to the neuroleptic treatment did not produce a statistically significant improvement of tardive dyskinesia in our patient population as a whole. Favorable and unfavorable responses are discussed.
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