Exogenous Surfactant Application in Respiratory Failure due to Chronic Obstructive Pulmonary Disease
作者:
Hubert Wirtz,
Wolfgang Habscheid,
Georg Ertl,
Michael Schmidt,
Kurt Kochsiek,
期刊:
Respiration
(Karger Available online 1995)
卷期:
Volume 62,
issue 3
页码: 157-159
ISSN:0025-7931
年代: 1995
DOI:10.1159/000196413
出版商: S. Karger AG
关键词: Pulmonary surfactant;Chronic obstructive pulmonary disease;Weaning
数据来源: Karger
摘要:
Recent results of basic research on regulation of surfactant secretion and surfactant physiology not only in the alveolus but also in peripheral small airways allow the conclusion that disorders in surfactant homeostasis may contribute to the pathophysiology of airway obstruction and hyperinflation. We therefore hypothesized that patients with respiratory failure due to obstructive lung disease may benefit from exogenous surfactant. Here we report a case that indicates the clinical situation to be considered for treatment with exogenous surfactant. The benefit for the patient was successful weaning from the ventilator. Improvements in effective compliance, resistance and blood gas parameters were observed following surfactant application.
点击下载:
PDF
(583KB)
返 回