A liquid chromatography system is directly coupled to a moderate power helium microwave induced plasma for the selective determination of no metals in aqueous solutions. The detector is a large volume helium microwave-induced plasma operated at 500 watts with a helium support gas flow of 21L/min. A sample set of halides and oxohalgen salts are separated by ion exchange chromatography and introduced into the plasma as mist generated with an ultrasonic nebulizer. Detection limits range from 1.5 to 6 μg. Calibration plots are presented. Selectivity is observed when monitoring the elemental signals of co-eluting peaks.