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Octreotide Effects on Orthostatic Hypotension in Patients with Multiple System AtrophyA Controlled Study of Acute Administration

 

作者: R. Bordet,   J. Benhadjali,   A. Destée,   A. Belabbas,   C. Libersa,  

 

期刊: Clinical Neuropharmacology  （OVID Available online 1995）
卷期: Volume 18, issue 1  

页码: 83-89

 

ISSN:0362-5664

 

年代: 1995

 

出版商: OVID

 

关键词: Octreotide;Orthostatic hypotension;Multiple system atrophy;Parkinsonism;norepinephrine

 

数据来源: OVID

 

摘要:

In nine patients with orthostatic hypotension due to multiple system atrophy, the effects of octreotide (100 μg s.c.), a somatostatin analogue, on blood pressure (BP), heart rate (HR), and norepinephrine (NE) plasma levels after 60° head up hit test were evaluated by a randomly controlled study. Octreotide increased sapine BP, tilt-test duration (+ 28%), and delay to obtain minimal BP during the 60° head up tilt (+ 50%). Octreotide changed neither HR nor NE plasma levels.

 

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