Acute Renal Failure in Pregnancy
作者:
AlexopoulosEfstathios,
TambakoudisPanagiotis,
BiliHelen,
SakellariouGeorge,
MantalenakisSergios,
PapadimitriouMenelaos,
期刊:
Renal Failure
(Taylor Available online 1993)
卷期:
Volume 15,
issue 5
页码: 609-613
ISSN:0886-022X
年代: 1993
DOI:10.3109/08860229309069411
出版商: Taylor&Francis
数据来源: Taylor
摘要:
Between 1982 and 1992, 18 cases of pregnancy-related acute renal failure (PR-ARF) were observed (9% of the total number of ARF). Mean age of the women was 32 years (22–40 years). Uterine hemorrhage andpreeclampsialeclampsia were the major causes of ARF, accounting for 61% of the cases. Patchy renal cortical necrosis was suspected in 2 cases whereas signs of disseminated intravascular coagulation (DIC) or microangiopathic hemolytic anemia were present in 6 (33%) and 9 (50%) cases, respectively. Ten women required hemodialysis; and 6 of them, additional plasma exchange sessions. Five patients (28%) died during the acute phase of the illness, mainly due to brain damage, hepatic failure, and sepsis. Among the survivors, a complete (61.5%) or partial recovery (23.1%) was usually seen, but irreversible renal failure was recorded in 2 cases with postpartum hemolytic uremic syndrome (HUS). Short-lasting oligoanuria (<3 days) represents a good prognostic index. However, the presence of vascular injury (cortical necrosis, HUS) seems to carry a poor prognosis. In conclusion, PR-ARF is still a critical occurrence, associated with serious prognosis for both women and kidneys. So far, the most effective measures remain the careful prevention and the aggressive management of the obstetric complications.
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