AbstractChanges in the amino acid fraction of buffered extracts of cod muscle during incubation in the presence of α‐ketoglutarate have been studied using a14C‐labelled amino acid mixture. The patterns of radioactive amino acids pre and post incubation suggest that transamination reactions are responsible for marked changes in the levels of aspartic acid, glutamic acid, alanine, valine, leucine and iso‐leucine. No changes were noted in the levels of threonine, serine, proline, glycine, lysine and arginine. Slight falls in the concentration of tyrosine and phenylalanine were seen after extended incubation