Hepatitis A-Induced Diabetes Mellitus, Acute Renal Failure, and Liver Failure
作者:
David Vesely,
Roger Dilley,
William Duckworth,
Frederick Paustian,
期刊:
The American Journal of the Medical Sciences
(OVID Available online 1999)
卷期:
Volume 317,
issue 6
页码: 419-419
ISSN:0002-9629
年代: 1999
出版商: OVID
关键词: Hepatitis A;RNA virus;Diabetes mellitus;Acute renal failure;Hepatic failure.
数据来源: OVID
摘要:
A 38-year-old otherwise healthy man presented with hepatic failure (aspartate aminotransferase of 7212 U/L, alanine aminotransferase of 6629 U/L, total and direct bilirubin of 10.7 mg/dL) and acute renal failure (creatinine of 11.6 mg/dL and blood urea nitrogen of 42 mg/dL), which required hemodialysis when the creatinine increased to 21 mg/dL, with a blood urea nitrogen of 115 mg/dL, and the patient became oliguric. On admission, this patient also had a lipase of 1833 U/L, amylase of 211 U/L, glucose of 210 mg/dL, and reactive IgM antibody for acute hepatitis A. The hepatitis and acute renal failure resolved in 3 months, but this patient continues to have type II diabetes mellitus 7 years after the hepatitis A infection. This case illustrates that hepatitis A infection may be severe with liver failure, acute renal failure, and permanent diabetes mellitus as sequale of this infection.
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