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von Willebrand's Disease in Scandinavia and on Difficulties in Diagnosing von Willebrand's Disease Type I

 

作者: Margareta Blombäck,  

 

期刊: Pathophysiology of Haemostasis and Thrombosis  （Karger Available online 1992）
卷期: Volume 22, issue 5  

页码: 236-244

 

ISSN:1424-8832

 

年代: 1992

 

DOI:10.1159/000216329

 

出版商: S. Karger AG

 

关键词: von Willebrand’s disease, type I and III;Scandinavia;Heredity;Diagnosis

 

数据来源: Karger

 

摘要:

The research on von Willebrand’s disease performed in Sweden and Finland since the late 1920s is reviewed. The difficulties in diagnosing mild von Willebrand’s disease, due to intra-individual variability, is discussed in relation to making correct pedigrees for genetic studies. As shown by some examples, new techniques for genetic studies will eliminate such difficulties and lead to better understanding of the pathogenesis.

 

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