A randomized, double-blind, comparative study of terbinafinevsgriseofulvin in tinea capitis
作者:
HaroonTS,
HussainI,
AmanS,
NagiAH,
AhmadI,
ZahidM,
AlviKH,
Iqba1N,
KhanKA,
期刊:
Journal of Dermatological Treatment
(Taylor Available online 1992)
卷期:
Volume 3,
issue sup1
页码: 25-27
ISSN:0954-6634
年代: 1992
DOI:10.3109/09546639209088698
出版商: Taylor&Francis
数据来源: Taylor
摘要:
An open clinical pilot study of terbinafine (Lamid®) in patients with tinea capitis had suggested that this agent was effective and well tolerated in the treatment of patients with this indication. On this basis, a double-blind randomized study comparing the efficacy and tolerability of terbinafine, given once daily for 4 weeks, and griseofulvin, given once daily for 8 weeks, was initiated. A 4-week placebo wash-out period separated the two active-treatment periods. Although this study is still in progress and the codes have not yet been broken, clinical and laboratory evaluation of 30 patients suggests that short-term (4-week) therapy with terbinafine is as effective and safe as 8 weeks of griseofulvin therapy in patients, including children, with tinea capitis.
点击下载:
PDF (198KB)
返 回