Hepatitis C Virus in Chronic Hemodialysis Patients with Non-A, Non-B Hepatitis
作者:
Clara Fumiko Tachibana Yoshida,
Clarina Takahashi,
Ana Maria Coimbra Gaspar,
Hermann G. Schatzmayr,
Frederico Ruzany,
期刊:
Nephron
(Karger Available online 1992)
卷期:
Volume 60,
issue 2
页码: 150-153
ISSN:1660-8151
年代: 1992
DOI:10.1159/000186731
出版商: S. Karger AG
关键词: Non-A;non-B hepatitis;Hepatitis C virus;Hemodialysis
数据来源: Karger
摘要:
Sixteen of 110 hemodialysis (HD) patients fulfilling criteria of non-A, non B hepatitis (NANBH), i.e. alanine aminotransferase (ALT) > 50 U/ml in the absence of both serologic markers for acute HBV and HAV infections and clinical evidence of another cause of hepatitis, were tested for the presence of antibodies against hepatitis C virus (anti-HCV) by enzyme immunoassay (Ortho, Diagnostics). All (100%) were anti-HCV-positive. There were 5 patients with a monophasic (M) rise pattern (1 or 2 ALT rises), and 11 cases demonstrated a polyphasic (P) rise elevation pattern (more than 2). The mean ALT value of the M group was 202.3 ± 209 U/ml and that of the P group was 116.6 ± 39.1 U/ml. The patients received a mean of 19.1 ± 16.2 units of packed red cells during the follow-up period (69.9 months). Only 1 patient received no blood transfusion. Six patients had a past HBV infection and 3 became HIV-infected in the course of this study. The high rate of infection of hemodialysis patients with hepatitis C virus in our setting points to the need for improved control measur
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