Determination of Ethylene Glycol Tissue Content After Fatal Oral Poisoning and Pathologic Findings
作者:
Philippe Hantson,
Roger Vanbinst,
Paul Mahieu,
期刊:
The American Journal of Forensic Medicine and Pathology
(OVID Available online 2002)
卷期:
Volume 23,
issue 2
页码: 159-161
ISSN:0195-7910
年代: 2002
出版商: OVID
关键词: Ethylene glycol;Poisoning;Tissue concentration;Postmortem determination
数据来源: OVID
摘要:
A 23-year-old comatose man who had drunk an unknown amount of ethylene glycol was admitted to the hospital 5 hours after ingestion. The initial plasma ethylene glycol concentration was 116.2 mg/100 ml. A severe metabolic acidosis was present. Despite aggressive therapy with ethanol, hemodialysis, and intensive care support, the patient died 27 hours after poisoning. The plasma ethylene glycol concentration immediately before death was 35.9 mg/100 ml. Brain edema and acute renal tubular necrosis were evident at postmortem examination. Oxalate crystals were identified in both organs. Ethylene glycol content or concentration was determined in tissues and biologic fluids.
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