Virus-Specific RNA Specified by the Group I and IV Temperature-Sensitive Mutants of Vesicular Stomatitis Virus
作者:
Stanley M. Perlman,
Alice S. Huang,
期刊:
Intervirology
(Karger Available online 1973)
卷期:
Volume 2,
issue 5-6
页码: 312-325
ISSN:0300-5526
年代: 1973
DOI:10.1159/000149439
出版商: S. Karger AG
关键词: Vesicular stomatitis virus;Replication and transcription;Temperature-sensitive mutants
数据来源: Karger
摘要:
Temperature-sensitive mutants of vesicular stomatitis virus were examined for their ability to synthesize intracellular virus-specific RNA species at the nonpermissive temperature. Four mutants from complementation group I (ts 11, ts 12, ts 13, ts 114) were compared to two mutants from complementation group IV (ts 41, ts 44). Mutants within one group did not resemble each other in their phenotypes; nevertheless, two distinct pathways of RNA synthesis were detected: one for transcription and the other for replication.
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